**I looked through the first eight pages of topics (going back to 2010) and didn't see this, so forgive me if it's a duplicate.
Seeing as this is a group for older anime fans, I thought it might be fun to list/discuss/recommend anime where the main characters (if not all, or most of the characters) are adults. There are tons of anime that have high school age characters, but there are also lots with adults as well.
For this topic, I'm defining 'adult' as anyone older than high school age.
Here's a few anime with a largely adult cast that I like:
Cowboy Bebop
Probably don't need to say too much about this. Nearly everyone has heard of it/seen it. It's very highly regarded (it often shows up on 'best anime of all time' lists) and nearly all the cast, both major and minor characters (aside from Radical Edward) are adults.
Baccano!
Mayhem galore in this non-linear, time skipping anime. Ultra violent, lots of fun, and everyone is an adult
even Cheslaw, who may look like a 10 year old, but is really somewhere around 230 years old.
Appare-Ranman!
A criminally overlooked anime that fell victim to production being paused during the pandemic shutdowns. It's really fun, lots of character development. and a really great time overall. The main character is one of the youngest (around age 19-20), and there's a kid around age 10-12, but everyone else is an adult.
Shirobako
Comedic workplace anime about an anime studio and everything involved with making anime. Lots of in-jokes, and an all-adult cast.
The Eccentric Family
On my top-five all time favorite anime list. A family of shape-shifting tanuki in Kyoto adapting to life after the unexpected death of their father. Really odd and delightful, kind of talky at times and with more magical realism than you'll know what to do with! The main character (the second youngest of four brothers) is a young adult, probably around 20-21 (when in human form). The majority of the rest of the cast is adult.
Pet
Dark, disturbing psychological anime about people who enter other people's minds and mess with their memories for various reasons. All adult cast.
Inuyashiki
Disturbing sci-fi series. The main character is in his upper 50's. There are some high school kids (the second main character), but it has a dark, adult feel overall.
I guess by some technicality, Honey & Clover is a good cast of College adults. (With a slightly questionable younger looking female college student.) Yet delves into good mature topics. (Discuss Semantics?)
Others that I like to give mention are the following:
- Nodame Cantabille
- Golden Time
- Barakamon
- Ya Boy Kongming
- Maison Ikkokku
- Trigun
- Mushishi
Good topic. The older I get the more I find myself seeking out shows with adult casts. Luckily mal introduced an 'adult cast' tag making them easier to uncover. Off the top of my head there's also Gintama (excluding Shinpachi and Kagura almost everyone is an adult), City Hunter, Dirty Pair, Genshiken, Working and Black Lagoon.
Bartender: Glass of God is a new anime with an all adult cast. Two episodes have aired so far, and it's pretty good. A low-key yet somewhat ridiculous slice of life/workplace drama.
I like those live-action J-dramas and K-dramas. Some of those might have been based on a manga/anime.
If you want something old that's like mid-life crisis, there's Legend of Black Heaven (Kacho Oji)
20th Century Boys has mostly adults as the protagonists although they do flashback to when they were kids, and there's one section where the teenage daughter stars in a story arc. That's a manga but they have a live-action for that too.